Even though migraine is a common disease—the National Institute of Neurological Disorders and Strokes says it affects more than 10% of people around the world—it wasn’t fully understood until lately.
Doctors used to think that migraine symptoms were caused by changes in the way blood flowed through the brain. Now, though, scientists know that the pain and other signs of a migraine are caused by a mix of chemicals and hormones like serotonin and estrogen.
How a migraine works?
Migraines are not just headaches. It is a brain-based disease of the nervous system. The Association of Migraine Disorders says that people with migraines have a nervous system that is too sensitive and overreacts to certain triggers, such as stress, hormone changes, lack of sleep, being dehydrated, or certain foods or drinks.
Everyone has different causes, but they all set off the same chain of events: First, the trigeminal nerve, which starts in the brain and goes all over the face, gets swollen and inflamed. This makes pain feel like it’s coming from both the face and the brain.
Most of the time, it causes a sharp pain on one side of the head, where the trigeminal artery widens. But the head pain can be so bad that it causes other migraine symptoms, like feeling sick.
Another common migraine sign is sensitivity to light, which is also called photophobia. Light can make the pain of a migraine worse by stimulating nerve cells between the eyes and in certain parts of the brain.
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According to a report that came out in the European Journal of Neuroscience in 2021, photophobia, or a fear of sounds, may be caused by nerve activation in the brain stem.
Some patients have problems with their nerves, like tingling in their face or arms, or sometimes they have trouble speaking.
How to Stop and Stop Migraine Attacks Before They Start?
If you feel a migraine coming on, try to stop it before it starts. Most experts agree that the best way to treat a migraine is as soon as possible after it starts.
With an over-the-counter pain reliever like aspirin, acetaminophen, or a nonsteroidal anti-inflammatory drug (NSAID) like naproxen or ibuprofen, you may be able to stop or at least lessen a migraine. Use these with care, though, because the American Migraine Foundation says that taking them more than 15 days a month could fail and cause headaches from too much medicine.
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Talk to your doctor about getting a prescription for a migraine drug like a triptan or calcitonin gene-related peptide (CGRP) inhibitor if over-the-counter medicines don’t help. Triptans work by narrowing the trigeminal artery, which stops pain signals from reaching the brain.
However, because they also narrow other vessels, they can cause side effects like a red face or a tight chest. CGRP inhibitors stop the CGRP protein from doing its job, which is to send pain signals during a migraine attack. They don’t usually have any side effects.
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They will be able to find the right treatment and start it right away. Preventive drugs, like beta-blockers, calcium channel blockers, anti-seizure drugs, botulinum toxin injections, and CGRP inhibitors, can be helpful for some people.